Resveratrol Suppresses Gut-Derived NLRP3 Inflammasome Partly through Stabilizing Mast Cells in a Rat Model.

Weicheng ZhaoXiaolei HuangXue HanDan HuXiaohuai HuYuantao LiPin-Jie Huang Weifeng Yao

Published in: Mediators of inflammation (2018)

In summary, these findings reveal that resveratrol suppressed IIR injury by stabilizing MCs, preventing them from degranulation, accompanied with intestinal mucosa NLRP3 inflammasome inhibition and intestinal epithelial cell apoptosis reduction.

Keyphrases

nlrp inflammasome
cell proliferation
signaling pathway
genome wide
single cell