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Effects of a high-phosphate diet on vascular calcification and abdominal aortic aneurysm in mice.

Aya KomuroBo-Kyung SonMichiko Nanao-HamaiZehan SongSumito OgawaMasahiro Akishita
Published in: Geriatrics & gerontology international (2024)
These findings suggest that HPD induces vascular calcification and AAA formation, possibly through inflammation. This murine model suggests that vascular calcification induced by phosphate burden may be a therapeutic target for vascular diseases, including AAA. Geriatr Gerontol Int 2024; ••: ••-••.
Keyphrases
  • abdominal aortic aneurysm
  • chronic kidney disease
  • oxidative stress
  • physical activity
  • weight loss
  • type diabetes
  • metabolic syndrome
  • high fat diet induced