Derivation and utility of an Aβ-PET pathology accumulation index to estimate Aβ load.
Antoine LeuzyJohan LiljaChristopher J BuckleyRik OssenkoppeleSebastian PalmqvistMark BattleGill FarrarDietmar Rudolf ThalShorena JanelidzeErik StomrudOlof StrandbergRuben SmithOskar HanssonPublished in: Neurology (2020)
This study provides Class III evidence that the Aβ accumulation index accurately differentiates Aβ-positive from Aβ-negative participants compared to Aβ-PET visual reads, CSF Aβ42/Aβ40, and Aβ histopathology.