Radiological-pathological signatures of patients with COVID-19-related pneumomediastinum: is there a role for the Sonic hedgehog and Wnt5a pathways?

Elisa BaratellaRossana BussaniFabrizio ZanconatiCristina MarrocchioGiudici FabiolaLuca BragaSerena MaiocchiGiorgio BerlotMaria Concetta VolpeEdoardo MoroPaola ConfalonieriMaria Assunta CovaMarco ConfalonieriFrancesco SaltonBarbara Ruaro

Published in: ERJ open research (2021)

Pneumomediastinum is a rare complication of ARDS but is more common during #COVID19. The fibrous hyaline degeneration of the tracheal rings seen in this autoptic series is an original observation that has not been previously described in COVID-19 patients. https://bit.ly/3vxTQde.

Keyphrases

sars cov
acute respiratory distress syndrome
stem cells
cell proliferation
extracorporeal membrane oxygenation
mechanical ventilation
genome wide
dna methylation
drug induced