Subspecialized breast pathologists have suboptimal interobserver agreement in Ki-67 evaluation using 20% as the cutoff.

Di AiGulisa TurashviliSandra Gjorgova GjeorgjievskiQun WangAbdulwahab M EwazYuan GaoThi NguyenChao ZhangXiaoxian Li

Published in: Breast cancer research and treatment (2023)

The modified IKWG algorithm does not significantly improve interobserver agreement. A better algorithm or assistance from digital image analysis is needed to improve interobserver variability in Ki-67 evaluation.

Keyphrases

machine learning
deep learning
neoadjuvant chemotherapy
squamous cell carcinoma
neural network
rectal cancer