Autophagy-related CMTM6 promotes glioblastoma progression by activating Wnt/β-catenin pathway and acts as an onco-immunological biomarker.

Lirui DaiJingjia XiaoXiang LiYiran TaoPeizhi ZhouLiang LyuZimin ShiXianyin LiangZiyang JiaShu Jiang

Published in: The journal of gene medicine (2024)

Autophagy-related CMTM6 is highly expressed in various types of cancer, especially GBM, and it can regulate GBM progression through the Wnt/β-catenin signaling pathway and is capable of being used as an underlying target for the diagnosis, treatment selection and prognosis of patients with GBM.

Keyphrases

signaling pathway
cell death
cell proliferation
endoplasmic reticulum stress
oxidative stress
papillary thyroid
lymph node metastasis
smoking cessation