Exosomes from miRNA-126-modified endothelial progenitor cells alleviate brain injury and promote functional recovery after stroke.
Jinju WangShuzhen ChenWenfeng ZhangYanfang ChenJi Chen BihlPublished in: CNS neuroscience & therapeutics (2020)
Our results indicate that enrichment of miR126 enhanced the therapeutic efficacy of EPC-EXs on diabetic ischemic stroke by attenuating acute injury and promoting neurological function recovery.
Keyphrases
- brain injury
- subarachnoid hemorrhage
- cerebral ischemia
- liver failure
- cell proliferation
- long non coding rna
- mesenchymal stem cells
- respiratory failure
- type diabetes
- long noncoding rna
- stem cells
- atrial fibrillation
- endothelial cells
- aortic dissection
- drug induced
- wound healing
- intensive care unit
- bone marrow
- extracorporeal membrane oxygenation