Comprehensive Analysis Identifies Variability in PI3K Pathway Alterations in Triple-Negative Breast Cancer Subtypes.
Reva K BashoLi ZhaoJason B WhiteLei HuoRoland L BassettElizabeth A MittendorfAlastair ThompsonJennifer K LittonNaoto Tada UenoBanu K ArunBora LimVicente ValeroDebasish TripathyJianhua ZhangBeatriz E AdradaLumarie SantiagoElizabeth RavenbergSahil SethClinton YamStacy L MoulderSenthil DamodaranPublished in: JCO precision oncology (2024)
PI3K pathway alteration can affect response to NAT in TNBC, and targeted agents may improve outcomes, particularly in patients with M and LAR TNBC.