Branched-chain amino acid supplementation impairs insulin sensitivity and promotes lipogenesis during exercise in diet-induced obese mice.

Hongsong ZhangLi XiangMingyu HuoYalan WuMingyang YuChi Wai LauDanyang TianLingshan GouYuhong HuangJiang-Yun LuoLi WangWencong SongJuan HuangZongwei CaiShaoliang ChenXiao Yu TianYu Huang

Published in: Obesity (Silver Spring, Md.) (2022)

BCAA supplementation impaired the beneficial effect of exercise on glycolipid metabolism in obese but not lean mice. Caution should be taken regarding the use of BCAAs for individuals with obesity who exercise.

Keyphrases

high intensity
high fat diet induced
physical activity
weight loss
metabolic syndrome
amino acid
type diabetes
resistance training
insulin resistance
body composition
bariatric surgery