Coadministration of Canagliflozin and Phentermine for Weight Management in Overweight and Obese Individuals Without Diabetes: A Randomized Clinical Trial.

Priscilla A HollanderHarold E BaysJulio RosenstockMary Ellen FrustaciAlbert FungFrank VercruysseNgozi Erondu

Published in: Diabetes care (2017)

CANA/PHEN produced meaningful reductions in body weight and was generally well tolerated in individuals who were overweight or obese without type 2 diabetes. Further studies are warranted to evaluate potential use of this combination for long-term weight management.

Keyphrases

body weight
type diabetes
weight loss
glycemic control
physical activity
weight gain
cardiovascular disease
body mass index
bariatric surgery
adipose tissue
metabolic syndrome
insulin resistance
risk assessment
obese patients
case control
human health