Transcriptional regulation in the rat prefrontal cortex and hippocampus after a single administration of psilocybin.
Oskar Hougaard JefsenBetina ElfvingGregers WegenerHeidi Kaastrup MüllerPublished in: Journal of psychopharmacology (Oxford, England) (2020)
The present study demonstrates that psilocybin rapidly induces gene expression related to neuroplasticity, biased towards the prefrontal cortex, compared to the hippocampus. Our findings provide further evidence for the rapid plasticity-promoting effects of psilocybin.