Investigation of the Relationship Between Susceptibility Loci for Hip Osteoarthritis and Dual X-Ray Absorptiometry-Derived Hip Shape in a Population-Based Cohort of Perimenopausal Women.
Denis A BairdLavinia PaternosterJennifer S GregoryBenjamin G FaberFiona R SaundersClaudiu V GiuraniucRebecca J BarrDeborah A LawlorRichard M AspdenJonathan H TobiasPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2018)
Hip OA susceptibility loci were associated with shape in this study, suggesting that these loci (and potentially yet-to-be-identified hip OA loci) could contribute to hip OA in later life via perturbing biologic pathways that mediate morphology development.
Keyphrases
- total hip arthroplasty
- genome wide
- genome wide association study
- knee osteoarthritis
- genome wide association
- rheumatoid arthritis
- dual energy
- high resolution
- dna methylation
- type diabetes
- magnetic resonance imaging
- postmenopausal women
- gene expression
- bone mineral density
- metabolic syndrome
- magnetic resonance
- adipose tissue
- skeletal muscle
- mass spectrometry
- cervical cancer screening