Association of urine and plasma ADMA with atherosclerotic cardiovascular disease risk in diabetic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) study.
Sarah J SchraubenHima SapaDawei XieXiaoming ZhangAmanda Hyre AndersonMichael G ShlipakChi-Yuan HsuTariq ShafiRupal MehtaZeenat BhatJulie BrownJeanne CharlestonJing ChenJiang HeJoachim H IxPandurango RaoRay TownsendPaul L KimmelRamachandran S VasanHarold I FeldmanJesse C SeegmillerHenri BrunengraberThomas H HostetterJeffrey R Schellingnull nullPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2023)
These data suggest that decreased kidney excretion of ADMA leads to increased plasma concentrations and ASCVD risk.