Development of a biomarker prediction model for post-trauma multiple organ failure/dysfunction syndrome based on the blood transcriptome.
Ivan DuranAnkita BanerjeePatrick J FlahertyYok-Ai QueColleen M RyanLaurence G RahmeAmy TsurumiPublished in: Annals of intensive care (2024)
The accurate assessment of MOF from blood samples immediately after trauma is expected to aid in improving clinical decision-making and may contribute to reduced morbidity, mortality and healthcare costs. Moreover, understanding the molecular mechanisms involving the transcripts identified as important for MOF prediction may eventually aid in developing novel interventions.