Brain FDG-PET findings in chimeric antigen receptor T-cell therapy neurotoxicity for diffuse large B-cell lymphoma.

Silvia MorbelliMassimiliano GambellaAnna Maria RaiolaChiara GhiggiMatteo BaucknehtTania Di RaimondoCaterina LapucciGianmario SambucetiMatilde IngleseEmanuele Angelucci

Published in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2023)

Patients with ICANS are characterized by a frontolateral hypometabolic signature coherently with the hypothesis of ICANS as a predominant frontal syndrome and with the more prominent susceptibility of frontal lobes to cytokine-induced inflammation.

Keyphrases

diffuse large b cell lymphoma
functional connectivity
resting state
pet ct
positron emission tomography
epstein barr virus
pet imaging
working memory
oxidative stress
diabetic rats
high glucose
computed tomography
white matter
case report
drug induced
cerebral ischemia
stem cells
cell therapy