Comprehensive laboratory assessment of lonoctocog alfa versus octocog alfa in severe haemophilia A.

Jens MüllerThilo AlbertClaudia KleinSilvia HorneffHeiko RühlBernd PötzschGeorg GoldmannNatascha MarquardtJohannes Oldenburg

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2024)

Lonoctocog alfa and octocog alfa showed comparable recovery and safety in vivo as well as similar impacts on TG in vitro. Observed assay discrepancies on lonoctocog alfa demonstrated variability of results also between different FVIII CSAs.

Keyphrases

replacement therapy
smoking cessation
high throughput
drug induced