Glutamate Transmission to Ventral Tegmental Area GABA Neurons Is Altered by Acute and Chronic Ethanol.

Stephanie B WilliamsJordan T YorgasonAshley C NelsonNatalie LewisTeresa M NuferJeff G EdwardsScott C Steffensen

Published in: Alcoholism, clinical and experimental research (2018)

These results suggest that presynaptic mechanisms involving local circuit GLU neurons, and not GLU receptors, contribute to adaptations in VTA GABA neuron excitability that accrue to ethanol exposure, which may contribute to the rewarding properties of alcohol via their regulation of mesolimbic dopamine transmission.

Keyphrases

spinal cord
liver failure
drug induced
respiratory failure
prefrontal cortex
spinal cord injury
high intensity
deep brain stimulation
uric acid
transcranial direct current stimulation
intensive care unit
mechanical ventilation