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Identification of vital modules and genes associated with heart failure based on weighted gene coexpression network analysis.

Weikang BianZhicheng WangXiaobo LiXiao-Xin JiangHongsong ZhangZhizhong LiuDai-Min Zhang
Published in: ESC heart failure (2022)
To the best of our knowledge, our study is the first to employ WGCNA to identify the key module and hub genes for HF. Our study identified a module and two genes that might play important roles in HF, which may provide potential biomarkers for the diagnosis of HF and improve our knowledge of the molecular mechanisms underlying HF.
Keyphrases
  • network analysis
  • heart failure
  • acute heart failure
  • healthcare
  • bioinformatics analysis
  • genome wide
  • magnetic resonance
  • genome wide identification
  • left ventricular
  • atrial fibrillation
  • copy number
  • contrast enhanced