COVID-19 associated with extensive pulmonary arterial, intracardiac and peripheral arterial thrombosis.
Katie FergusonNathaniel QuailPeter KewinKevin G BlythPublished in: BMJ case reports (2020)
We describe a patient with COVID-19 who developed simultaneous pulmonary, intracardiac and peripheral arterial thrombosis. A 58-year-old man, without major comorbidity, was admitted with a 14-day history of breathlessness. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection was confirmed by laboratory testing. Initial imaging revealed COVID-19 pneumonia but no pulmonary thromboembolism (PTE) on CT pulmonary angiography (CTPA). The patient subsequently developed respiratory failure and left foot ischaemia associated with a rising D-dimer. Repeat CTPA and lower limb CT angiography revealed simultaneous bilateral PTE, biventricular cardiac thrombi and bilateral lower limb arterial occlusions. This case highlights a broad range of vascular sequalae associated with COVID-19 and the fact that these can occur despite a combination of prophylactic and treatment dose anticoagulation.
Keyphrases
- respiratory syndrome coronavirus
- coronavirus disease
- lower limb
- sars cov
- pulmonary hypertension
- respiratory failure
- case report
- pulmonary embolism
- computed tomography
- extracorporeal membrane oxygenation
- high resolution
- magnetic resonance imaging
- single cell
- atrial fibrillation
- mechanical ventilation
- intensive care unit
- positron emission tomography
- acute respiratory distress syndrome
- magnetic resonance
- dual energy
- fluorescence imaging