Microglial dynamics after axotomy-induced retinal ganglion cell death.

Francisco M Nadal-NicolásManuel Jiménez-LópezManuel Salinas-NavarroPaloma Sobrado-CalvoManuel Vidal-SanzMarta Agudo-Barriuso

Published in: Journal of neuroinflammation (2017)

Axotomy-induced RGC death occurs earlier than RGC clearance and there is an inverse correlation between RGC loss and PMC appearance, both numerically and topographically, suggesting that phagocytosis occurs as a direct response to RGC death rather than to axonal damage.

Keyphrases

cell death
high glucose
diabetic rats
oxidative stress
spinal cord injury
drug induced
inflammatory response
endothelial cells
spinal cord
stress induced