PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age.
Renata SenkerikovaSona FrankovaMilan JirsaMiluse KreidlovaDusan MertaMagdalena NeroldovaKlara ChmelovaJulius SpicakJan SperlPublished in: PloS one (2019)
Our results suggest that PNPLA3 rs738409 G allele carriage may be associated with a faster progression of HCV cirrhosis to chronic liver failure.