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Tranexamic Acid Use in the Surgical Arena: A Narrative Review.

Anaas Moncef MergoumAdel S MergoumNicholas J LarsonDavid J DriesAlan CookBenoit BlondeauFrederick B Rogers
Published in: The Journal of surgical research (2024)
The administration of TXA as an adjunct to treat trauma saves lives. The ability of TXA to induce seizures is dose dependent with identifiable risk factors, making this serious adverse effect predictable. As for the potential for TXA to cause thrombotic events, uncertainty remains. If this association is proven to be real, the risk will likely be small, since the use of TXA is still advantageous in most situations because of its efficacy for a more common concern, bleeding.
Keyphrases
  • risk factors
  • atrial fibrillation
  • risk assessment
  • human health
  • adverse drug
  • electronic health record