Toll-like receptor 5-mediated signaling enhances liver regeneration in mice.

Wen ZhangLei WangXue-Hua SunXian LiuYang XiaoJie ZhangTing WangHui ChenYi-Qun ZhanMiao YuChang-Hui GeChang-Yan LiGuang-Ming RenRong-Hua YinXiao-Ming Yang

Published in: Military Medical Research (2021)

We reveal that TLR5 activation contributes to the initial events of liver regeneration after PHx. Our findings demonstrate that TLR5 signaling positively regulates liver regeneration and suggest the potential of TLR5 agonist to promote liver regeneration.

Keyphrases

toll like receptor
stem cells
inflammatory response
nuclear factor
immune response
wound healing
genome wide
gene expression
metabolic syndrome
human health