Histomorphological and inflammatory changes of white adipose tissue in gastrointestinal cancer patients with and without cachexia.

Alessio MolfinoRaffaella CarlettiGiovanni ImbimboMaria Ida AmabileRoberta BelliCira R T di GioiaElena BelloniFrancesco SpinelliVeronica RizzoCarlo CatalanoGiuseppe NigriMaurizio Muscaritoli

Published in: Journal of cachexia, sarcopenia and muscle (2021)

We found histological alterations of SAT among gastrointestinal cancer patients and in particular significant changes in CSA, fibrosis, and inflammation when cachexia was present; the changes in histomorphological parameters of the adipocytes reflected alterations in adiposity at body composition analysis.

Keyphrases

body composition
adipose tissue
insulin resistance
oxidative stress
resistance training
bone mineral density
papillary thyroid
high fat diet
type diabetes
skeletal muscle
physical activity
high intensity
liver fibrosis
childhood cancer