Light/Palladium-Promoted Benzylic C-H Acylation Using a Benzoyl Group as the Photo-Directing Group.

Yusuke Masuda Naoki Ishida Masahiro Murakami

Published in: Chemistry, an Asian journal (2019)

2-Methylphenyl ketones undergo site-selective acylation at the benzylic position when treated with acid anhydride under UV irradiation in the presence of a palladium catalyst. The benzoyl carbonyl group serves as the photo-directing group so that the ortho benzylic C-H bond is activated site-selectively.

Keyphrases

reduced graphene oxide
newly diagnosed
carbon dioxide
aqueous solution