HeMoQuest: a webserver for qualitative prediction of transient heme binding to protein motifs.
Ajay Abisheck Paul GeorgeMauricio LacerdaBenjamin Franz SyllwasschyMarie-Thérèse HoppAmelie WißbrockDiana ImhofPublished in: BMC bioinformatics (2020)
Heme plays a crucial role as a regulatory molecule exerting functional consequences via transient binding to surfaces of target proteins. HeMoQuest is designed to address this imperative need for a computational approach that enables rapid detection of heme-binding motifs from protein datasets. While most existing implementations attempt to predict sites of permanent heme binding, this application is to the best of our knowledge, the first of its kind to address the significance of predicting transient heme binding to proteins.