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An Exploratory Analysis of Routine Ferritin Measurement Upon Admission and the Prognostic Implications of Low-Grade Ferritinemia During Inflammation.

Rafael Y BrzezinskiAsaf WassermanNoa SassonMoshe StarkIlana GoldinerOri RogowskiShlomo BerlinerOri Argov
Published in: The American journal of medicine (2024)
Routine admission ferritin concentrations are linearly and independently correlated with excess mortality risk in hospitalized patients, even those with apparently "normal" ferritin concentrations (<300 mg/mL). Thus, low-grade ferritinemia might not be an innocent finding in the context of the inflammatory response. Its potential biological and therapeutic implications warrant future research.
Keyphrases
  • low grade
  • inflammatory response
  • high grade
  • emergency department
  • clinical practice
  • iron deficiency
  • oxidative stress
  • lipopolysaccharide induced
  • current status
  • lps induced
  • toll like receptor
  • immune response