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Selective Fluorogenic Sensing of As(III) Using Aptamer-Capped Nanomaterials.

Mar OrovalCarmen CollAndrea BernardosMaría D MarcosRamón Martínez-MáñezDmitry G ShchukinFélix Sancenón
Published in: ACS applied materials & interfaces (2017)
Organic-inorganic hybrid nanomaterials offer extremely valuable tools for monitoring many types of analytes in solution. Within this framework, aptamer-based nanomaterials for heavy metal detection are still very scarce. Herein, a novel sensing nanoprobe for the selective and sensitive detection of As(III) based on the combination of aptamers with mesoporous silica nanoparticles has been developed. The efficiency of the sensor is demonstrated in environmental conditions, showing a great potential in As(III) monitoring assays.
Keyphrases
  • sensitive detection
  • loop mediated isothermal amplification
  • quantum dots
  • heavy metals
  • label free
  • gold nanoparticles
  • human health
  • risk assessment
  • high throughput
  • water soluble
  • health risk