Atypical lipomatous tumour/well-differentiated liposarcoma and de-differentiated liposarcoma in patients aged ≤ 40 years: a study of 116 patients.
Rebecca WatersAndrew HorvaiPatricia GreippIvy JohnElizabeth G DemiccoBrendan C DicksonMunir R TanasBrandon T LarsenNasir Ud DinDavid H CreytensArmita BahramiLeona A DoyleVickie Y JoAlyaa Al-IbraheemiKhin ThwaySarah M JenkinsBrittany SiontisAndrew L FolpeKaren J FritchiePublished in: Histopathology (2019)
ALT/WDL and DDLPS occurring in patients aged ≤ 40 years is rare, but exhibits similar morphological features to its counterparts in older adults, including potential for heterologous and homologous de-differentiation in the latter. Although case numbers are limited, tumours arising in the head and neck exhibit high rates of adverse events, suggesting that classification as WDL rather than ALT is more appropriate.