Concatemer Assisted Stoichiometry Analysis (CASA): targeted mass spectrometry for protein quantification.

Jiaxi Cai Quan YunCindy Yuxuan ZhangZiyi WangStephen P Hinshaw Huilin Zhou Raymond T Suhandynata

Published in: bioRxiv : the preprint server for biology (2024)

This study presents Concatemer-Assisted Stoichiometry Analysis (CASA) to address a common challenge in cell biological research: quantifying the number of each protein subunit in a native protein complex.

Keyphrases

mass spectrometry
protein protein
amino acid
stem cells
high resolution
cancer therapy
mesenchymal stem cells
small molecule
bone marrow
ms ms
simultaneous determination
tandem mass spectrometry
data analysis