Placental Expression of ACE2 and TMPRSS2 in Maternal Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Are Placental Defenses Mediated by Fetal Sex?

Lydia L ShookEvan A BordtMarie-Charlotte MeinsohnDavid PepinRose M De GuzmanSara BrigidaLaura J YockeyKaitlyn E JamesMackenzie W SullivanLisa M BebellDrucilla J RobertsAnjali J KaimalJonathan Z LiDanny SchustKathryn J GrayAndrea G Edlow

Published in: The Journal of infectious diseases (2021)

Sex differences in placental TMPRSS2 but not ACE2 were observed in the setting of maternal SARS-CoV-2 infection, which may have implications for offspring vulnerability to placental infection.

Keyphrases

respiratory syndrome coronavirus
sars cov
coronavirus disease
angiotensin converting enzyme
birth weight
angiotensin ii
pregnancy outcomes
climate change
type diabetes
skeletal muscle
body mass index
pregnant women
physical activity
weight loss