Prognostic value of total, free and lipoprotein fraction-bound plasma mitotane levels in advanced adrenocortical carcinoma: a prospective study of the ENDOCAN-COMETE-Cancer network.

Matthieu FaronA NamanJ DelahousseS HescotJ HadouxF CastinettiD DruiP Renoult-PierreR LibeL LamartinaS LeboulleuxA Al-GhuzlanM LombèsA PaciE Baudinnull null

Published in: Journal of endocrinological investigation (2024)

This prospective study did not identify any added prognostic value of free mitotane level over the total level. Early total mitotane level measurements (before 3-6 months) were related to OS with a higher and faster exposure related to more prolonged survival.

Keyphrases

papillary thyroid
young adults