Randomized Clinical Trial of Intravenous (IV) Acetaminophen as an Adjunct to IV Hydromorphone for Acute Severe Pain in Emergency Department Patients.

Polly E Bijur Benjamin W FriedmanDeborah WhiteAndrew WollowitzCaron CampbellMichael P JonesAndrew K ChangE John Gallagher

Published in: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2020)

The addition of 1 g of IV acetaminophen to 1 mg of IV hydromorphone provided neither clinically meaningful nor statistically superior analgesia than hydromorphone alone.

Keyphrases

emergency department
liver injury
drug induced
pain management
end stage renal disease
newly diagnosed
ejection fraction
chronic pain
early onset
prognostic factors
neuropathic pain
spinal cord
spinal cord injury
low dose
ultrasound guided
adverse drug
double blind
electronic health record