Nuclear pore pathology underlying multisystem proteinopathy type 3-related inclusion body myopathy.

Rumiko IzumiKensuke IkedaTetsuya NiihoriNaoki SuzukiMatsuyuki ShirotaRyo FunayamaKeiko NakayamaHitoshi WaritaMaki TateyamaYoko AokiMasashi Aoki

Published in: Annals of clinical and translational neurology (2023)

The shared subset of altered NUPs in amyotrophic lateral sclerosis (ALS), as demonstrated in prior research, HNRNPA1-mutated, and HNRNPA1-unlinked hIBM muscle tissues may provide evidence regarding the underlying common nuclear pore pathology of hIBM, ALS, and MSP.

Keyphrases

amyotrophic lateral sclerosis
gene expression
skeletal muscle
plasmodium falciparum
muscular dystrophy