Variants of concern responsible for SARS-CoV-2 vaccine breakthrough infections from India.

Urvashi B SinghMercy RophinaRama ChaudhryVigneshwar SenthivelKiran BalaRahul C BhoyarBani JollyNayer JamshedMohamed ImranRitu GuptaPraveen AggarwalMohit Kumar DivakarSubrata SinhaV R ArvindenAnjali BajajAfra ShamnathAbhinav Jainnull nullVinod ScariaSridhar SivasubbuRandeep Guleria

Published in: Journal of medical virology (2021)

Emerging reports of SARS-CoV-2 breakthrough infections entail methodical genomic surveillance for determining the efficacy of vaccines. This study elaborates genomic analysis of isolates from breakthrough infections following vaccination with AZD1222/Covishield and BBV152/Covaxin. Variants of concern B.1.617.2 and B.1.1.7 responsible for cases surge in April-May 2021 in Delhi, were the predominant lineages among breakthrough infections.

Keyphrases

sars cov
copy number
public health
emergency department
gene expression
drug induced