Lack of an atypical PDR transporter generates an immunogenic Cryptococcus neoformans strain that drives a dysregulated and lethal immune response in murine lungs.
Christopher J WinskiPeter V StuckeyArmando M MarrufoRobbi L RossGeorgina AgyeiSarah ChapmanFelipe Hiram Santiago-TiradoPublished in: bioRxiv : the preprint server for biology (2024)
in modulating antifungal sensitivity and immune responses, this work provides important insights that may lead to new or improved therapeutics.