Cytochrome 2B6 polymorphism and efavirenz-induced central nervous system symptoms : a substudy of the ANRS ALIZE trial.
Sébastien GallienV JournotM-A LoriotH SauvageonP MorlatJ ReynesV ReliquetG ChêneJ-M Molinanull nullPublished in: HIV medicine (2017)
The deficient CYP2B6 516 T allele is associated with higher efavirenz plasma drug levels and more frequent CNS-related symptoms.