Successful autologous hematopoietic stem cell transplantation in a refractory anti-Caspr1 antibody nodopathy.

Vadim AfanasievPinelopi TsouniThierry KuntzerAnne CairoliEmilien DelmontJean-Michel VallatJérôme DevauxMarie Théaudin

Published in: Journal of the peripheral nervous system : JPNS (2024)

We report a particularly severe anti-Caspr1 antibody autoimmune nodopathy that responded dramatically to AHSCT. Although the rarity of the disease limits the possibility of larger studies, AHSCT may be a valuable therapy in treatment-refractory cases.

Keyphrases

multiple sclerosis
bone marrow
early onset
drug induced
stem cells
replacement therapy
smoking cessation