Proteinuria and Clinical Outcomes in Hospitalized COVID-19 Patients: A Retrospective Single-Center Study.
Alexandre KarrasMarine LivrozetHélène LazarethNicolas BenichouJean-Sébastien HulotAntoine FayolSophie ChauvetAnne-Sophie JannotMarie-Aude PenetJean-Luc DiehlAnne GodierOlivier SanchezTristan MiraultEric ThervetNicolas PalletPublished in: Clinical journal of the American Society of Nephrology : CJASN (2021)
Proteinuria is very frequent among patients admitted for COVID-19 and may precede AKI. Low levels of albuminuria suggest a predominant tubular origin, confirmed by the elevated levels of urine retinol binding protein. Urine protein-creatinine ratio ≥1 g/g at admission is strongly associated with poor kidney and patient outcome.