Evaluating the frequency and the impact of pharmacogenetic alleles in an ancestrally diverse Biobank population.

Shefali S VermaKarl KeatBinglan LiGlenda HoffeckerMarjorie Rismannull nullKatrin SangkuhlMichelle Whirl-CarrilloScott DudekAnurag VermaTeri E KleinMarylyn D RitchieSony Tuteja

Published in: Journal of translational medicine (2022)

Clinically actionable PGx alleles are highly prevalent in our health system and many patients were prescribed medications that could be affected by PGx alleles. These results illustrate the potential utility of preemptive genotyping for tailoring of medications and implementation of PGx into routine clinical care.

Keyphrases

healthcare
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
quality improvement
primary care
prognostic factors
high throughput
genome wide
gene expression
patient reported outcomes
pain management
climate change
patient reported
chronic pain
health insurance
single cell