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Risk of treatment-altering haematological toxicity and its dependence on bone marrow doses in peptide receptor radionuclide therapy.

Märta PerssonCecilia HindorfOscar ArdenforsMartin LarssonJoachim N Nilsson
Published in: EJNMMI research (2024)
Treatment-altering haematological toxicity in peptide receptor radionuclide therapy is relatively rare and appears difficult to fully predict from post-therapeutic image-based dosimetry. However, for patients with skeletal metastases, the haematological dose-response relationships are stronger. Future studies may focus on this patient group, to further investigate the usefulness of dosimetry in predicting decreases in blood values.
Keyphrases
  • bone marrow
  • oxidative stress
  • mesenchymal stem cells
  • deep learning
  • stem cells
  • machine learning
  • combination therapy
  • current status
  • replacement therapy
  • binding protein