Genomic profile of metastatic breast cancer patient-derived xenografts established using percutaneous biopsy.

Seongyeong KimDongjin ShinAhrum MinMinjung KimDeukchae NaHan-Byeol LeeHan Suk RyuYaewon YangGo-Un WooKyung-Hun LeeDae-Won LeeTae-Yong KimCharles LeeSeock-Ah ImJong-Il Kim

Published in: Journal of translational medicine (2021)

Our PDX model was established using core needle biopsy samples from primary and metastatic tissues. Genomic profiles of the samples reflected their original tissue characteristics and could be used for the interpretation of clinical outcomes.

Keyphrases

ultrasound guided
metastatic breast cancer
fine needle aspiration
copy number
squamous cell carcinoma
small cell lung cancer
gene expression
dna methylation