The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice.
Khaled GreishAbdulelah Abdullah AlqahtaniAbdulla Falah AlotaibiAhmed Mohamed AbdullaAysha Tariq BukellyFanar Mohammed AlsobyaniGhazi Hamad AlharbiIsraa Saeed AlkiyumiMajed Mutlaq AldawishTurki Fahad AlshahraniValeria PittalaSebastien TaurinAmer KamalPublished in: International journal of environmental research and public health (2019)
Silver Nanoparticles (AgNPs), an epitome of nanotechnology, appear in everyday products such as water filters, printer ink, toothpaste, food packaging and cosmetics mostly due to their bactericidal properties. Given this high level of public exposure, the safety of AgNPs has never been fully established. The unsafe use of AgNPs could pose a real threat, not only to public health but also to economic growth in many industries. In this paper, we tested the effect of AgNPs on memory, learning, social behaviour and motor function of BALB/C mice. Outcomes of the present study suggested an impairment of these functions in AgNPs treated groups. Overall, obtained data support the evidence that the systemic exposure to AgNPs may result in alteration of the cerebral cognition and warrants further consideration on the impact of the AgNPs on human health with respect to their potential neurotoxicity.
Keyphrases
- silver nanoparticles
- human health
- public health
- risk assessment
- healthcare
- mental health
- working memory
- climate change
- emergency department
- multiple sclerosis
- high fat diet induced
- machine learning
- electronic health record
- subarachnoid hemorrhage
- metabolic syndrome
- deep learning
- blood brain barrier
- data analysis
- glycemic control