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Evaluation of Breast Implant-associated Anaplastic Large Cell Lymphoma With Whole Exome and Genome Sequencing.

Neha AkkadRohan KodguleEric J DuncavageNeha Mehta-ShahDavid H SpencerMarcus P WatkinsCara ShiraiTerence Myckatyn
Published in: Aesthetic surgery journal (2022)
While no recurrent mutations were identified our study identified mutations in genes not previously reported with BIA-ALCL or other forms of ALCL. Furthermore, not previously reported with BIA-ALCL, 11q22.3 deletions were consistent across whole genome sequencing cases and present in some exomes.
Keyphrases
  • single cell
  • genome wide
  • cell therapy
  • diffuse large b cell lymphoma
  • copy number
  • gene expression
  • mesenchymal stem cells
  • soft tissue
  • transcription factor
  • bone marrow
  • genome wide identification
  • genome wide analysis