A highly acute disease broke out in ducklings in Shandong Province in March 2019. The disease was characterized as visceral gout, with a mortality rate of 30%. The causative agent, which has given rise to similar symptoms in goslings, has been confirmed to be a novel goose astrovirus. The novel goose astrovirus, which was designated as the SDXT strain, was identified from a diseased duck farm using duck embryo primary cells in an experimental infection test. Genomic sequence analysis, as well as phylogenetic analysis of the viral proteins, revealed that the SDXT strain was closely related to a novel goose astrovirus of the Avastrovirus three species. These results indicate that the novel goose astrovirus may cross-host infect ducklings. Further studies are needed to define its host range and transmission route.
Keyphrases
- induced apoptosis
- liver failure
- cell cycle arrest
- south africa
- single cell
- cardiovascular events
- type diabetes
- gene expression
- oxidative stress
- copy number
- cell death
- drug induced
- intensive care unit
- skeletal muscle
- adipose tissue
- coronary artery disease
- metabolic syndrome
- cell proliferation
- pi k akt
- signaling pathway
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- data analysis
- genetic diversity