Cardiopulmonary bypass (CPB) is an essential technique in cardiac surgery but is also associated with adverse effects, including the systemic inflammatory response syndrome that manifests itself as ischaemia-reperfusion injury and multi-organ dysfunction. The aim of this mini review is to take a look at the current knowledge of resveratrol, a stilbenoid and natural antioxidant believed to have many cardioprotective effects including vasodilation, lowering of blood pressure and reactive oxygen species levels, suppression of low-density lipoprotein peroxidation, and mitigation of ischaemia/-reperfusion injury. We mostly focus on its cardioprotective potential in patients undergoing cardiac surgery supported by CPB. Current findings, however, are still inconclusive and call for further research, including clinical trials.
Keyphrases
- cardiac surgery
- acute kidney injury
- inflammatory response
- oxidative stress
- low density lipoprotein
- blood pressure
- reactive oxygen species
- patients undergoing
- clinical trial
- cerebral ischemia
- acute myocardial infarction
- healthcare
- anti inflammatory
- climate change
- acute ischemic stroke
- lipopolysaccharide induced
- human health
- case report
- heart failure
- type diabetes
- coronary artery disease
- risk assessment
- percutaneous coronary intervention
- skeletal muscle
- lps induced
- left ventricular
- blood glucose
- metabolic syndrome
- acute coronary syndrome