TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence.
Yao YuDan FanXinmao SongKaveh ZakeriLinda ChenJung Julie KangSean Matthew McBrideChiaojung Jillian TsaiLara DunnEric ShermanNora KatabiSnjezana DoganJennifer CracchioloMarc CohenJay O BoyleMark LeeCristina ValeroJingming WangRichard WongLuc G T MorrisNadeem RiazNancy Y LeePublished in: JCO precision oncology (2021)
TERT promoter status is associated with the cumulative incidence of LRF and patterns of failure. TERT promoter mutations may define a subset of OSCCs with unique pathogenesis that is associated with an increased risk of LRF. Validation in prospective cohorts is warranted.