TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence.
Yao YuDan FanXinmao SongKaveh ZakeriLinda ChenJung Julie KangSean Matthew McBrideChiaojung J TsaiLara DunnEric ShermanNora KatabiSnjezana DoganJennifer CracchioloMarc CohenJay O BoyleMark LeeCristina ValeroJingming WangRichard WongLuc G T MorrisNadeem RiazNancy Y LeePublished in: JCO precision oncology (2021)
TERT promoter status is associated with the cumulative incidence of LRF and patterns of failure. TERT promoter mutations may define a subset of OSCCs with unique pathogenesis that is associated with an increased risk of LRF. Validation in prospective cohorts is warranted.