Novel 3D in vitro models to evaluate trophoblast migration and invasion.

Yuan YouPatrick StelzlYonghong ZhangJames PorterHong LiuAi-Hua LiaoPaulomi B AldoGil Mor

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2019)

We report the characterization of 3D in vitro models to evaluate the interaction between endometrial cells and trophoblast during the process of migration and invasion. The models are useful tools in order to further study the molecular mechanism of embryo-maternal uterine cells interactions.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
cell death
oxidative stress
pregnant women
physical activity
cell proliferation
endometrial cancer
weight gain