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Hemophagocytic lymphohistiocytosis in Egyptian children: diagnosis, treatment challenges, and outcome.

Azza A TantawyNayera H K ElsherifSolaf M ElsayedHeba G A AliSara M MakkeyahHisham I E ElsantielGeneviève de Saint BasileIman Ahmed Ragab
Published in: Expert review of hematology (2024)
This study confirms that the nonspecific signs and symptoms of HLH are challenging. Genetic testing, though expensive and sophisticated, is integral for the diagnosis. The difficulty in finding non-related donors for stem cell transplantation and the early reactivations are the causes of the inferior outcome.
Keyphrases
  • stem cell transplantation
  • high dose
  • young adults
  • replacement therapy
  • smoking cessation