Detection of Antimicrobial Resistance Genes Associated with Carbapenem Resistance from the Whole-Genome Sequence of Acinetobacter baumannii Isolates from Malaysia.
Mohan RaoFairuz A RashidSurianti ShukorRohaidah HashimNorazah AhmadPublished in: The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale (2020)
Most of the isolates were grouped under the CC92 clonal complex which belongs to international clonal lineage 2. These findings predict that carriage of carbapenem-resistant genes possibly constitutes the underlying basis of high level of international clone II prevalence. Therefore, molecular surveillance and antimicrobial stewardship are essential in implementing policies to prevent and control the spread of CrAb in hospital settings.
Keyphrases
- acinetobacter baumannii
- antimicrobial resistance
- multidrug resistant
- drug resistant
- pseudomonas aeruginosa
- public health
- healthcare
- gram negative
- genome wide
- risk factors
- klebsiella pneumoniae
- single cell
- quality improvement
- loop mediated isothermal amplification
- cystic fibrosis
- acute care
- label free
- adverse drug
- real time pcr
- dna methylation
- cell fate